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Efficacy and safety of nivolumab combined with standard therapies for first-line therapy of advanced non-small cell lung cancer

   
@article{JTD10037,
	author = {Martin Metzenmacher and Daniel C. Christoph},
	title = {Efficacy and safety of nivolumab combined with standard therapies for first-line therapy of advanced non-small cell lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {8},
	number = {10},
	year = {2016},
	keywords = {},
	abstract = {In the last 10 years treatment of advanced non-small cell lung cancer (NSCLC) improved and progressed dramatically. Although platinum-based doublet is still state of the art as first-line therapy in most cases (1), patients experience prolonged progression-free survival (PFS) and extended overall-survival (OS) by adding maintenance therapy (2) and/or antiangiogenic drugs (in first- or secondline (3,4) to the cytostatic regime. NSCLC harboring an EGFR-“driver” mutation can be treated effectively, with moderate adverse events, by an oral tyrosine kinase inhibitor (TKI) (5,6) or a combination of TKI with the antiangiogenic drug bevacizumab (7), resulting in improved PFS and OS [in case of an exon 19 deletion (6)].},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/10037}
}