@article{JTD10402,
author = {Xin Zhang and Yukun Kuang and Yuan Zhang and Kai He and Noah Lechtzin and Mingying Zeng and Rex C. Yung and Canmao Xie},
title = {Shifted focus of bronchoalveolar lavage in patients with suspected thoracic malignancy: an analysis of 224 patients},
journal = {Journal of Thoracic Disease},
volume = {8},
number = {11},
year = {2016},
keywords = {},
abstract = {Background: Bronchoscopies are extensively adopted for diagnosing and staging thoracic malignancies, but studies are missing as how to keep the process streamlined and more efficient. To evaluate current role of bronchoalveolar lavage (BAL) for cancer and possible infection diagnosis when practicing comprehensive bronchoscopy for patients suspected with thoracic malignancy, and provide foundation for possible practice modification.
Methods: We retrospectively analyzed a prospectively kept database of immunocompetent patients undergoing bronchoscopy for suspected non-hematologic malignancies. Clinical, radiographic data, bronchoscopic sampling techniques and diagnostic results were recorded. Initially undiagnostic patients were followed up for 2 years for a definitive diagnosis.
Results: Of 224 patients included, 179 (79.9%) were confirmed with active thoracic malignancies. BAL diagnostic yield of cancer based on different radiographic characters of target lesion are as follow: isolated lymphadenopathies 0%, central lesions 45.5%, peripheral masses (diameter ≥3 cm) 21.4%, peripheral large nodules (2≤ diameter },
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/10402}
}