@article{JTD11231,
author = {Jin Ge and Vivek Verma and Andrew Hollander and Corey Langer and Charles B. Simone II},
title = {Pemetrexed-induced radiation recall dermatitis in a patient with lung adenocarcinoma: case report and literature review},
journal = {Journal of Thoracic Disease},
volume = {8},
number = {12},
year = {2016},
keywords = {},
abstract = {Radiation recall dermatitis (RRD) is an inflammatory reaction in a previously irradiated field subsequent to the administration of pharmacologic or promoting agents. Herein, we describe a 47-year-old man with NSCLC who was treated with radiotherapy and pemetrexed-based chemotherapy three years prior to developing RRD upon resumption of pemetrexed-based chemotherapy. RRD with pemetrexed is rare and consists of five cases reported thus far. Although RRD is a rare phenomenon, it should be considered in any patient with dermatologic reactions that occur at the site of previous exposure to radiation therapy. When severe, RRD can pose a significant, and possibly life-threatening, impediment to the treatment and care of oncology patients. We discuss the time course, natural history, and management of this condition, as well as a connection to internal organ involvement, such as pneumonitis in thoracic oncology patients.},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/11231}
}