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Impact of maximum standardized uptake value of non-small cell lung cancer on detecting lymph node involvement in potential stereotactic body radiotherapy candidates

  
@article{JTD12759,
	author = {Shanyuan Zhang and Shaolei Li and Yuquan Pei and Miao Huang and Fangliang Lu and Qingfeng Zheng and Nan Li and Yue Yang},
	title = {Impact of maximum standardized uptake value of non-small cell lung cancer on detecting lymph node involvement in potential stereotactic body radiotherapy candidates},
	journal = {Journal of Thoracic Disease},
	volume = {9},
	number = {4},
	year = {2017},
	keywords = {},
	abstract = {Background: The retrospective study investigated the association between the maximum standardized uptake value (SUVmax) of primary tumor and lymph node involvement in potential stereotactic body radiotherapy (SBRT) candidates.
Methods: A total of 185 patients with clinical stage I NSCLC were enrolled in the current study. All patients underwent lobectomy with systematic lymph node dissection following preoperative FDG-PET/CT scanning. The association between clinicopathological variables and lymph node involvement was analyzed by univariate and multivariate analysis. Spearman’s correlation test was used to evaluate the correlation between them. Receiver operating characteristic (ROC) analysis was performed to calculate the area under the curve.
Results: Among these patients, 22.1% had occult lymph node involvement, 15.1% were N1 and 7.0% were N2. Greater tumor size (P=0.007), elevated CEA (P=0.006), central location (P=0.002), higher SUVmax (P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/12759}
}