TY - JOUR AU - Walter, Dirk PY - 2017 TI - Intratumoral heterogeneity of esophageal squamous cell carcinoma JF - Journal of Thoracic Disease; Vol 9, No 5 (May 28, 2017): Journal of Thoracic Disease Y2 - 2017 KW - N2 - The advent of large scale genome characterization led to rapidly increasing knowledge of genetic landscapes of malignancies in recent years. Besides a difference in quantity of mutations between different entities, studies revealed as well a difference in the amount of mutations in varying locations of a single neoplastic lesion: the relation of private (only present in a single sample of a tumor) and common mutations (present in all tested samples of tumor) can vary markedly (1-3). UR - https://jtd.amegroups.org/article/view/13494