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Durable complete response to nivolumab in a patient with HIV and metastatic non-small cell lung cancer

   
@article{JTD13605,
	author = {Brennan McCullar and Taylor Alloway and Michael Martin},
	title = {Durable complete response to nivolumab in a patient with HIV and metastatic non-small cell lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {9},
	number = {6},
	year = {2017},
	keywords = {},
	abstract = {Programmed death 1 (PD-1) inhibitors have been shown to increase overall survival in non-small cell lung cancer (NSCLC) patients. HIV patients have increased expression of PD-1 on their T-cell surfaces. We describe a patient with well-controlled HIV and NSCLC who underwent treatment with nivolumab and had a durable complete response (CR) with his viral load remaining undetectable. To date there is only one case report of a cancer patient with melanoma and with HIV treated with a programmed death ligand 1 (PD-L1) inhibitor. The majority of clinical trials involving PD-1 and PD-L1 inhibitors exclude HIV patients.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/13605}
}