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Should the cut-off value of D-dimer be elevated to exclude pulmonary embolism in acute exacerbation of COPD?

   
@article{JTD1376,
	author = {Evrim Eylem Akpınar and Derya Hoşgün and Beyza Doğanay and Gökçe Kaan Ataç and Meral Gülhan},
	title = {Should the cut-off value of D-dimer be elevated to exclude pulmonary embolism in acute exacerbation of COPD?},
	journal = {Journal of Thoracic Disease},
	volume = {5},
	number = {4},
	year = {2013},
	keywords = {},
	abstract = {Objective: The aim of this study was to evaluate the D-dimer levels in patients with chronic obstructive pulmonary disease (COPD) exacerbation with and without pulmonary embolism (PE) and to attempt to define a new cut-off value for D-dimer to exclude the diagnosis of PE in patients with COPD exacerbation.
Methods: This cross-sectional study was performed between the June 2012 and January 2013. The COPD patients who were admitted to the emergency department with acute exacerbation were consecutively included. D-dimer levels were measured upon admission. All patients underwent computed tomography angiography (CTA) and Doppler ultrasonography (US) of the lower extremities.
Results: A total of 148 patients were enrolled. Fifty-three patients (36%) who did not have PE had higher than normal (>0.5 pg/mL) D-dimer levels. The D-dimer levels of the COPD patients with PE were significantly higher than those of the patients without PE (2.38±2.80 vs. 1.06±1.51 pg/mL) (P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/1376}
}