@article{JTD1433,
author = {Peng Sun and Fei Zhang and Cui Chen and Xin An and Yu-Hong Li and Feng-Hua Wang and Zhi-Hua Zhu},
title = {Comparison of the prognostic values of various nutritional parameters in patients with esophageal squamous cell carcinoma from Southern China},
journal = {Journal of Thoracic Disease},
volume = {5},
number = {4},
year = {2013},
keywords = {},
abstract = {Background: Nutritional evaluation is important for patients with esophageal cancer, but the impact of undernutrition on outcome of those patients is not well elucidated. Our aim is to assess the impact of baseline nutritional status on overall survival (OS) in Chinese patients with esophageal squamous cell carcinoma (ESCC) and to detect a most appropriate indicator for nutritional evaluation.
Methods: 502 patients from Southern China diagnosed as ESCC in Sun Yat-Sen University Cancer Center were included. A series of nutritional indicators were introduced to evaluate the baseline nutritional status. Kaplan-Meier method was used to estimate the 5-year OS and the log-rank test was used to determine the survival differences. Cox proportional hazards model was used in the univariate and multivariate analyses of OS.
Results: With a median follow up time of 30 months, the median OS for the entire patient group was 37.3 months with the 5-year OS rate of 43.0%. Only performance status, AJCC 6th stage and body mass index (BMI) were the independent prognostic factors in multivariate analysis of OS. The median OS for patients with BMI less than 18.5, patients with BMI within 18.5-24.9 and patients with BMI more than 24.9 were 19.2, 43.2 and 51.6 months, respectively, with the 5-year OS rates of 25.2%, 46.1% and 48.1% (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/1433}
}