@article{JTD14759,
author = {Xiongfei Li and Renwang Liu and Tao Shi and Shangwen Dong and Fan Ren and Fan Yang and Dian Ren and Haiyang Fan and Sen Wei and Gang Chen and Jun Chen and Song Xu},
title = {Primary pulmonary malignant fibrous histiocytoma: case report and literature review},
journal = {Journal of Thoracic Disease},
volume = {9},
number = {8},
year = {2017},
keywords = {},
abstract = {Malignant fibrous histiocytoma (MFH) is an aggressive soft tissue sarcoma known to occur in various organs. Primary MFH arising in the lung is quite rare. Herein we report a case of a 61-year-old male with primary pulmonary MFH and explore the underlying molecular mechanisms by next-generation sequencing (NGS). Five gene mutations in TSC2, ARID1B, CDK8, KDM5C and CASP8 were detected, and the mTOR inhibitor might be an effective treatment for this patient. In addition, we reviewed the scientific literature of approximately 23 primary pulmonary MFH case reports since 1990 and summarized the clinical features and prognosis of this rare pulmonary malignant tumor.},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/14759}
}