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Unique distribution of programmed death ligand 1 (PD-L1) expression in East Asian non-small cell lung cancer

  
@article{JTD15037,
	author = {Yunjian Pan and Difan Zheng and Yuan Li and Xu Cai and Zongli Zheng and Yan Jin and Haichuan Hu and Chao Cheng and Lei Shen and Jian Wang and Hongbin Ji and Yihua Sun and Xiaoyan Zhou and Haiquan Chen},
	title = {Unique distribution of programmed death ligand 1 (PD-L1) expression in East Asian non-small cell lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {9},
	number = {8},
	year = {2017},
	keywords = {},
	abstract = {Background: To determine the proportion and clinical features of programmed death ligand 1 (PD-L1) expression in East Asian non-small cell lung cancer (NSCLC).
Methods: PD-L1 expression was assessed by immunohistochemistry (IHC) and tumor proportion score (TPS) with the use of PD-L1 IHC 22C3 antibody (Dako North America) in 108 surgically resected lung squamous cell carcinomas (SCC) and 221 lung adenocarcinomas (LUADs), and was correlated with clinical variables, histologic subtypes, and common driver mutations. 
Results: Positive PD-L1 expression was found in 37 lung SCC (37/108,34.3%), including 15 cases with TPS ≥50% (15/108, 13.9%) and 22 cases with TPS },
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/15037}
}