@article{JTD15043,
author = {Akash M. Patel and Ian Berger and E. Paul Wileyto and Urooj Khalid and Drew A. Torigian and Arun C. Nachiappan and Eduardo M. Barbosa Jr and Warren B. Gefter and Maya Galperin-Aizenberg and Narainder K. Gupta and Charles B. Simone II and Andrew R. Haas and Evan W. Alley and Sunil Singhal and Keith A. Cengel and Sharyn I. Katz},
title = {The value of delayed phase enhanced imaging in malignant pleural mesothelioma},
journal = {Journal of Thoracic Disease},
volume = {9},
number = {8},
year = {2017},
keywords = {},
abstract = {Background: Cross-sectional imaging of malignant pleural mesothelioma (MPM) can underestimate the presence of local tumor invasion. Since accurate staging is vital optimal choice of therapy, techniques that optimize pleural imaging are needed. Here we estimate the optimal timing of MPM enhancement on magnetic resonance imaging (MRI).
Methods: All MPM patients with intravenous (IV) contrast enhanced staging MRI between 2000–2016 at our institution were retrospectively selected for image analysis. Patients with incomplete imaging protocol and maximum pleural tumor thickness 80%, >85%, and >90% peak tumor enhancement. There was a statistically significant correlation between increasing tumor enhancement and subjective lesion conspicuity.
Conclusions: Optimal MPM enhancement on MRI likely occurs at a time delay between 2.5–5 min following IV contrast administration. Further study of delayed phase enhancement of MPM with dynamic contrast enhanced MRI is warranted.},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/15043}
}