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Worse survival after curative resection in patients with pathological stage I non-small cell lung cancer adjoining pulmonary cavity formation

  
@article{JTD15892,
	author = {Hiroyuki Kimura and Hisashi Saji and Tomoyuki Miyazawa and Hiroki Sakai and Masataka Tsuda and Yoichi Wakiyama and Hideki Marushima and Koji Kojima and Haruhiko Nakamura},
	title = {Worse survival after curative resection in patients with pathological stage I non-small cell lung cancer adjoining pulmonary cavity formation},
	journal = {Journal of Thoracic Disease},
	volume = {9},
	number = {9},
	year = {2017},
	keywords = {},
	abstract = {Background: A few investigators have suggested an association between lung cancer and pulmonary cavity. However, this clinical association and its carcinogenic correlations are not well recognized. This study aimed to clarify the clinical features and to demonstrate the associated survival outcomes after curative surgery in patients with early non-small cell lung cancer (NSCLC) adjoining pulmonary cavity formation.
Methods: We retrospectively reviewed 275 patients with pathological stage I NSCLC by re-evaluating their chest computed tomography images. Among them, we detected NSCLC adjoining pulmonary cavity formation in 12 (4.4%) patients.
Results: The median follow-up period for all 275 patients was 43.2 (range, 6.0–86.0) months. Of these patients, 6 (50.0%) in group CF (patients with NSCLC adjoining pulmonary cavity formation) and 19 (7.2%) in group C (the control group, n=263) died during the study period. Besides, 6 (50.0%) and 32 (12.2%) patients in groups CF and C, respectively, exhibited recurrence of the primary lung cancer. The cumulative overall survival (OS) in groups CF and C at 5 years was 37.0% and 91.7%, respectively (P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/15892}
}