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Atezolizumab in advanced non-small cell lung cancer

  
@article{JTD15955,
	author = {Marius Ilie and Paul Hofman},
	title = {Atezolizumab in advanced non-small cell lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {9},
	number = {10},
	year = {2017},
	keywords = {},
	abstract = {Atezolizumab (Tecentriq®, MPDL3280A, Genentech, CA, USA) is a humanized IgG1 antagonist antibody to PD-L1 engineered to avoid antibody-dependent cell-mediated cytotoxicity of activated T cells that may express PD-L1 (1). It blocks directly the interaction between the PD-L1 and PD-1/B7.1 receptors activation complex, hence it activates the tumor-specific immune response, and induces tumor cell killing (1).},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/15955}
}