@article{JTD1654,
author = {Kun Xiao and Long-Xiang Su and Bing-Chao Han and Peng Yan and Na Yuan and Jie Deng and Jia Li and Li-Xin Xie},
title = {Analysis of the severity and prognosis assessment of aged patients with community-acquired pneumonia: a retrospective study},
journal = {Journal of Thoracic Disease},
volume = {5},
number = {5},
year = {2013},
keywords = {},
abstract = {Background: Community-acquired pneumonia (CAP) is a prevalent and potentially life-threatening infection, and has poor prognosis in aged patients. The objective of this study was to compare the potential of admission N-terminal pro B-type natriuretic peptide (proBNP) levels and scoring models [CURB-65, Pneumonia Severity Index (PSI), and Acute Physiology and Chronic Health Evaluation (APACHE) II scores] to predict outcomes for aged patients with CAP admitted to Intensive Care Unit (ICU), and to explore the prognostic factors.
Methods: Clinical data of the patients were collected retrospectively, whose CURB-65, PSI, APACHE II scores were calculated and in whom measurements of proBNP was performed. The outcomes of interest were severity evaluation, prediction of need for mechanical ventilation and 28-day mortality. Receiver operating characteristic (ROC) curve was conducted to predict the assessment ability of proBNP and scoring models on different outcomes, and the logistic regression analysis was performed to screen factors affecting prognosis.
Results: 240 patients were enrolled, with the mean age of 75±8 years old. Admission levels of NT-proBNP, scoring models were significantly higher in SCAP patients, MV group, and non-survivors compared to non-SCAP patients, no-MV group, and 28-day survivors, respectively (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/1654}
}