@article{JTD17621,
author = {Inderpal Thethi and Shokufeh Ramirez and Wei Shen and Dingding Zhang and Maha Mohamad and Upendra Kaphle and Fayez Kheir},
title = {Effect of chest tube size on pleurodesis efficacy in malignant pleural effusion: a meta-analysis of randomized controlled trials},
journal = {Journal of Thoracic Disease},
volume = {10},
number = {1},
year = {2017},
keywords = {},
abstract = {Background: Malignant pleural effusion (MPE) develops in approximately 50% of all patients with metastatic cancer. The efficacy of small- vs. large-bore chest tube for pleurodesis in patients with MPE is still not clear.
Methods: We performed a meta-analysis to evaluate the efficacy and safety of chest tube size in the management of MPE. A systematic search of Medline (Ovid) and Embase (from 1980 to March 2016) was performed. Randomized clinical trials (RCTs) evaluating the effect of small (≤14 French) vs. large (>14 French) chest tube size on successful pleurodesis for patients with MPE. Of 708 potentially relevant publications, four matched the selection criteria and were included in the meta-analysis.
Results: Overall relative risk (RR) with 95% confidence intervals (CI) was pooled using a random-effects model. Heterogeneity was assessed using Q statistic (significant at P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/17621}
}