%0 Journal Article
%T Square peg, round hole? Programmed death-1 inhibitors in epidermal growth factor receptor-mutant non-small cell lung cancer
%A Gainor, Justin F.
%J Journal of Thoracic Disease
%D 2018
%B 2018
%9 
%! Square peg, round hole? Programmed death-1 inhibitors in epidermal growth factor receptor-mutant non-small cell lung cancer
%K 
%X Immune checkpoint inhibitors have emerged as powerful new agents in the management of advanced, non-small cell lung cancer (NSCLC). In particular, monoclonal antibodies targeting the programmed death-1 (PD-1) receptor and its ligand, PD-L1, have transformed treatment approaches for patients with advanced lung cancer. In a series of pivotal studies, the PD-1 inhibitors nivolumab and pembrolizumab and the PD-L1 inhibitor atezolizumab produced signi cant improvements in overall survival compared to standard single- agent chemotherapy in previously treated patients (1-4).
%U https://jtd.amegroups.org/article/view/18181
%V 10
%N 1
%P 25-29
%@ 2077-6624