@article{JTD18653,
author = {Chia-Chuan Liu and Bing-Yen Wang and Chih-Shiun Shih and Nicolas Pennarun and Lay-Chin Lim and Shi-Ying Gao and Chih-Tao Cheng},
title = {Comparison of survival between lung cancer patients receiving single or multiple-incision thoracoscopic surgery},
journal = {Journal of Thoracic Disease},
volume = {10},
number = {2},
year = {2018},
keywords = {},
abstract = {Background: The effect of single-incision thoracoscopic surgery for lung cancer on long-term survival is unknown and no studies have investigated whether there are differences in survival between single and multiple incision approaches. We aimed to compare long-term overall survival and disease-free survival of patients who underwent single-incision thoracoscopic surgery with those who received multiple-incision thoracoscopic surgery for lung cancer.
Methods: We retrospectively analyzed 532 patients with lung cancer who underwent either single-incision (n=150) or multiple-incision thoracoscopic resection (n=382) during the period January 2000 to December 2014. Patients were matched on propensity score at a 1:2 ratio to estimate the effect of treatment on longterm and disease-free survival. Overall survival and disease-free survival were assessed using the Kaplan- Meier method, the log-rank test and Cox proportional-hazards regression.
Results: Propensity matching resulted in 138 patients in the single-incision group and 276 patients in the multiple-incision group. The matched patients in the single-incision group had a significantly better 5-year overall survival than those in the multiple-incision group (P=0.027). Disease-free survival was similar between the two groups before and after matching. The number of chest wall incisions did not influence overall survival or disease-free survival.
Conclusions: The long-term outcomes of single-incision thoracoscopic surgery are comparable to those of multiple-incision thoracoscopic surgery for lung cancer.},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/18653}
}