%0 Journal Article %T Anti-angiogenic therapy in nonsquamous non-small cell lung cancer (NSCLC) with tyrosine kinase inhibition (TKI) that targets the VEGF receptor (VEGFR): perspective on phase III clinical trials %A Revels, Sha’Shonda L. %A Lee, Jay M. %J Journal of Thoracic Disease %D 2018 %B 2018 %9 %! Anti-angiogenic therapy in nonsquamous non-small cell lung cancer (NSCLC) with tyrosine kinase inhibition (TKI) that targets the VEGF receptor (VEGFR): perspective on phase III clinical trials %K %X Annually, there are over 200,000 lung cancer diagnoses in the United States (1). Only about 15% of patients are diagnosed with early stage disease (1). The prognosis of those with advanced disease, such as stage IIIB or stage IV, is dismal and less than 5% (1). The standard of care includes platinum based systemic therapy combinations. However, treatments are shifting toward newer targeted and small molecule therapies to improve outcomes among patients with advanced non-small cell lung cancer (NSCLC). %U https://jtd.amegroups.org/article/view/18878 %V 10 %N 2 %P 617-620 %@ 2077-6624