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Sodium bicarbonate on severe metabolic acidosis during prolonged cardiopulmonary resuscitation: a double-blind, randomized, placebo-controlled pilot study

   
@article{JTD20593,
	author = {Shin Ahn and Youn-Jung Kim and Chang Hwan Sohn and Dong Woo Seo and Kyoung Soo Lim and Michael W. Donnino and Won Young Kim},
	title = {Sodium bicarbonate on severe metabolic acidosis during prolonged cardiopulmonary resuscitation: a double-blind, randomized, placebo-controlled pilot study},
	journal = {Journal of Thoracic Disease},
	volume = {10},
	number = {4},
	year = {2018},
	keywords = {},
	abstract = {Background: Sodium bicarbonate administration during cardiopulmonary resuscitation (CPR) is controversial. Current guidelines recommend sodium bicarbonate injection in patients with existing metabolic acidosis, but clinical trials, particularly, those involving patients with acidosis, are limited. We aimed to evaluate the efficacy of sodium bicarbonate administration in out-of-hospital cardiac arrest (OHCA) patients with severe metabolic acidosis during prolonged CPR. 
Methods: Prospective, double-blind, randomized placebo-controlled pilot trial was conducted between January 2015 and December 2015, at a single center emergency department (ED). After 10 minutes of CPR, patients who failed to achieve return of spontaneous circulation (ROSC) and with severe metabolic acidosis (pH},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/20593}
}