@article{JTD24280,
author = {Yi Hu and Kong-Jia Luo and Jing Wen and Zhi-Hua Zhu},
title = {Strong expression of Id-1 in metastatic lymph nodes from esophageal squamous cell carcinoma is associated with better clinical outcome},
journal = {Journal of Thoracic Disease},
volume = {10},
number = {9},
year = {2018},
keywords = {},
abstract = {Background: Over-expression of inhibitor of differentiation or DNA binding 1 (Id-1) is associated with poor prognosis in esophageal squamous cell carcinoma (ESCC). However, some biomarkers discordant expression in metastasis has been reported previously. We aimed to confirm possible differential expression and prognostic value of Id-1 in paired metastatic lymph node (PMLN).
Methods: Expression of Id-1 in primary tumors (PT) and paired regional metastatic lymph nodes of ESCC were evaluated with immunohistochemical (IHC) analysis. Statistical analysis of Kaplan-Meier method was performed to test the prognostic significance of Id-1 expression.
Results: The expression of Id-1 was down-regulated in metastatic lymph nodes compared with primary esophageal tumors (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/24280}
}