@article{JTD24299,
author = {Hadil A. Al Otair and Fayez Elshaer and Alaa Elgishy and Samar Z. Nashwan and Aljohara S. Almeneessier and Awad H. Olaish and Ahmed S. BaHammam},
title = {Left ventricular diastolic dysfunction in patients with obesity hypoventilation syndrome},
journal = {Journal of Thoracic Disease},
volume = {10},
number = {10},
year = {2018},
keywords = {},
abstract = {Background: Obesity hypoventilation syndrome (OHS) can be complicated by several cardiovascular conditions. We assessed the prevalence and factors associated with left ventricular diastolic dysfunction (LVDD) in patients with OHS.
Methods: In this prospective observational study, all consecutive OHS patients referred to the sleep disorders clinic between January 2002 to December 2016 were included (n=113). Demographic data, echocardiography, sleep parameters, arterial blood gases (ABGs), and lung functions were recorded.
Results: Of 113 patients with OHS who participated, 76 patients (67%) had LVDD. More than twothirds had grade 1 LVDD. Median body mass index (BMI) was 42.8 kg/m2. Median PaCO2 was 55.8 mmHg. Median apnea hypopnea index (AHI) was 52 (25–38.5). Eighty-four (75.7%) patients were hypertensive, and 60 (54.1%) were diabetic. To minimize the effect of fluctuations in intrathoracic pressure during the obstructive respiratory events on the cardiac function, 38 OHS patients with mild to moderate OSA (AHI },
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/24299}
}