%0 Journal Article %T Successful treatment of lung adenocarcinoma with gefitinib based on EGFR gene amplification %A Wang, Chunguo %A Xu, Feng %A Shen, Jianfei %A Zhang, Linna %A Zhang, Jian %A Jin, Jiang %A Ampollini, Luca %A Schil, Paul van %A Kimura, Hideharu %A Grossi, Francesco %A Suda, Kenichi %A Zhang, Bo %A Ma, Dehua %A AME Lung Cancer Collaborative Group, written on behalf of the %J Journal of Thoracic Disease %D 2018 %B 2018 %9 %! Successful treatment of lung adenocarcinoma with gefitinib based on EGFR gene amplification %K %X In the past, the optimal first-line treatment of advanced non-small cell lung cancer (NSCLC) patients with wild-type for epidermal growth factor receptor (wt-EGFR) has been platinum-based chemotherapy doublets (1,2). More recently, clinicians have adopted immunotherapy with check-point inhibitors alone, in PD-L1 strong positive, or combined with chemotherapy independently to PD-L1 expression (3). %U https://jtd.amegroups.org/article/view/24888 %V 10 %N 11 %P E779-E783 %@ 2077-6624