TY  - JOUR
AU  - Turgut, Teyfik
AU  - İlhan, Nevin
AU  - Deveci, Figen
AU  - Akpolat, Nusret
AU  - Erden, Ersin Şükrü
AU  - Muz, M. Hamdi
PY  - 2014
TI  - Glutathione and nitrite levels in induced sputum at COPD patients and healthy smokers
JF  - Journal of Thoracic Disease; Vol 6, No 6 (June 26, 2014): Journal of Thoracic Disease
Y2  - 2014
KW  - 
N2  - Objectives: The role of oxidative stress at the pathogenesis of chronic obstructive pulmonary disease (COPD) is known. The aim of this study is to investigate the oxidative stress with sputum induction that is a simple method in COPD patients and healthy smokers.   Methods: Sputum induction was performed in 21 COPD patients (10 stable, 11 acute exacerbations), nine healthy smokers, and ten healthy non-smokers. Glutathione, NO2– levels, and cell counts at sputum, and plasma NO2– contents were evaluated in all subjects.   Results: Mean sputum glutathione and NO2– levels were significantly higher in acute exacerbations with COPD patients than healthy smokers (P=0.007 and P
UR  - https://jtd.amegroups.org/article/view/2537