@article{JTD25726,
author = {Jing Zhou and Xianhong Zhao and Xu Zhang and Xingmei Yu and Yuqing Wang and Wujun Jiang and Li Huang and Chuangli Hao and Luo Zhang},
title = {Values of fractional exhaled nitric oxide for cough-variant asthma in children with chronic cough},
journal = {Journal of Thoracic Disease},
volume = {10},
number = {12},
year = {2018},
keywords = {},
abstract = {Background: Chronic cough is a common symptom in children. We wished to explore the value of fractional exhaled nitric oxide (FeNO) for cough-variant asthma (CVA) in children with chronic cough.
Methods: This prospective cohort study was conducted in the Children’s Hospital of Soochow University from January 2012 to December 2014. Children aged 6–14 years with a cough of duration >4 weeks were enrolled. They underwent FeNO measurement, sputum cytology and pulmonary function tests.
Results: A total of 115 patients and 25 healthy controls were evaluated. For the diagnosis of CVA, the optimal FeNO cutoff value was 25 ppb with a sensitivity of 84.0%, specificity of 97.1%, positive predictive value of 97.5%, and negative predictive of being 81.4%. The FeNO level had a significant correlation with eosinophil count in sputum (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/25726}
}