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Changes in quality of life after surgery or radiotherapy in early-stage lung cancer

  
@article{JTD26041,
	author = {Rebecca M. Schwartz and Naomi Alpert and Kenneth Rosenzweig and Raja Flores and Emanuela Taioli},
	title = {Changes in quality of life after surgery or radiotherapy in early-stage lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {1},
	year = {2018},
	keywords = {},
	abstract = {Background: Although surgical resection is considered the standard of care for early-stage non-small cell lung cancer, radiotherapy [stereotactic body radiation therapy (SBRT)] has been proposed as a minimally invasive treatment alternative. Studies have not examined differences in quality of life (QoL) between surgery and radiotherapy, despite important implications for patient and provider decision making.
Methods: The Surveillance, Epidemiology, and End Results Medicare Health Outcomes Survey (1998–2014) was used to assess changes in physical QoL score [Physical Component Summary (PCS)] and mental health QoL score [Mental Component Summary (MCS)] from baseline (prior to cancer diagnosis) to follow-up after treatment with surgery only or radiotherapy only. QoL was measured using the 36-item Short Form Health Survey (SF-36) until 2006, when it was replaced by the Veterans RAND 12-Item Health Survey (VR-12). 
Results: Data from 184 patients (28 SBRT, 156 surgery) was included. There was a significant decline in PCS score from baseline to follow-up (surgery: −4.81; 95% CI: −6.31, −3.30; P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/26041}
}