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Current role and future direction of osimertinib in epidermal growth factor receptor-mutant non-small cell lung cancer

  
@article{JTD26164,
	author = {Byeong-Ho Jeong and Sang-Won Um},
	title = {Current role and future direction of osimertinib in epidermal growth factor receptor-mutant non-small cell lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {1},
	year = {2018},
	keywords = {},
	abstract = {Osimertinib (Tagrisso, AstraZeneca) is a third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI) that potently and irreversibly inhibits EGFR-TKI sensitizing mutations and the T790M mutation; the drug exhibits lower-level activity against wild-type EGFR (1). Recently, the AME Lung Cancer Collaborative Group summarized the current role of osimertinib and made recommendations as to how osimertinib could,},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/26164}
}