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Obstructive lung disease in smokers and never smokers: further insights in patient-related approach in lung cancer understanding

   
@article{JTD28362,
	author = {Marco Alifano},
	title = {Obstructive lung disease in smokers and never smokers: further insights in patient-related approach in lung cancer understanding},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {Suppl 9},
	year = {2019},
	keywords = {},
	abstract = {Although smoking still represents the leading cause of lung cancer, obstructive lung disease is another independent risk factor. In chronic obstructive pulmonary disease (COPD), a systemic inflammatory disorder with specific tumor immune environment, this risk is two- to five-fold greater compared with smoking without COPD (1,2). Thus, when managing patients with non-small cell lung cancer (NSCLC) for curative treatment, (surgery, but also immune check points inhibitors in non-surgical patients), associated COPD should be taken into account, because of increased post-operative risk (3-6) on one side, but possible increased efficacy of anti PD1/PDL1 immunotherapy (7).},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/28362}
}