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Performance evaluation of MR-proadrenomedullin and other scoring systems in severe sepsis with pneumonia

  
@article{JTD2837,
	author = {Serdar Akpinar and Kazım Rollas and Ali Alagöz and Fatih Seğmen and Tuğrul Sipit},
	title = {Performance evaluation of MR-proadrenomedullin and other scoring systems in severe sepsis with pneumonia},
	journal = {Journal of Thoracic Disease},
	volume = {6},
	number = {7},
	year = {2014},
	keywords = {},
	abstract = {Background: In sepsis, risk assessment is as crucial as early and accurate diagnosis. In this study, we aimed to evaluate the prognostic value of mid-regional proadrenomedullin (MR-proADM) with other scoring systems in severe sepsis and septic shock patients due to community acquired pneumonia (CAP). 
Methods: Patients were divided into 2 groups as severe sepsis and septic shock due to CAP (group 1, n=31) and only CAP group (group 2, n=26). Serum MR-proADM, procalcitonin (PCT), C-reactive protein (CRP), and d-dimer level were analyzed. Acute Physiological and Chronic Health Evaluation (APACHE) II score, Sequential Organ Failure Assessment (SOFA) score, and Pneumonia Severity Index (PSI) were performed for all patients. 
Results: There was no difference between groups in terms of serum MR-proADM levels (P=0.780). Serum MR-proADM was not found a significant value for the prediction of death within the 4 and 8 weeks in all patients. SOFA score was the most significant to predict mortality in 4 and 8 weeks (P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/2837}
}