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Prognostic factors in patients with recurrence after complete resection of esophageal squamous cell carcinoma

  
@article{JTD2839,
	author = {Xiao-Dong Su and Dong-Kun Zhang and Xu Zhang and Peng Lin and Hao Long and Tie-Hua Rong},
	title = {Prognostic factors in patients with recurrence after complete resection of esophageal squamous cell carcinoma},
	journal = {Journal of Thoracic Disease},
	volume = {6},
	number = {7},
	year = {2014},
	keywords = {},
	abstract = {Background: Recurrence following complete resection of esophageal squamous cell carcinoma (SCC) still remains common. The aim of this study was to investigate the prognostic factors in patients with recurrence after complete resection of esophageal SCC. 
Methods: The medical records of 190 patients with recurrent disease after complete resection of esophageal SCC were retrospectively reviewed. Recurrence pattern was classified as loco-regional recurrence and distant metastases. The Kaplan-Meier method was used for the survival analysis. Cox proportional hazards model was used for multivariate analysis. 
Results: Mediastinal nodal clearance area was the most common sites of loco-regional recurrence, whereas lung, liver and bone were the most common sites for distant metastases. The median survival after recurrence was 8 months. The 1, 3, 5-year post-recurrence survival rates were 45.9%, 10.6% and 6.4%, respectively. The overall 1, 3, 5-year survival rates were 76.6%, 27.3% and 12.3%, respectively. The independent prognostic factors included time of recurrence (≥12 months vs. },
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/2839}
}