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The use of surgery in a real-world clinic to diagnose and treat pulmonary cryptococcosis in immunocompetent patients

  
@article{JTD28416,
	author = {Bumhee Yang and Hyun Lee and Taebum Lee and Sun-Hyung Kim and Min Young Kim and Byeong-Ho Jeong and Sumin Shin and Seonwoo Kim and Kyung Soo Lee and O. Jung Kwon and Hojoong Kim},
	title = {The use of surgery in a real-world clinic to diagnose and treat pulmonary cryptococcosis in immunocompetent patients},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {4},
	year = {2019},
	keywords = {},
	abstract = {Background: We evaluated the role played by surgery in the diagnosis and treatment of pulmonary cryptococcosis (PC) in immunocompetent subjects.
Methods: We retrospectively studied 53 immunocompetent patients who were pathologically diagnosed with PC between January 2000 and December 2016 in a tertiary referral center. We compared the radiological presentations of, and diagnostic modalities used to evaluate, patients diagnosed both surgically and non-surgically. We also compared the treatment outcomes of patients who underwent surgical resection alone and those who received additional antifungals following surgical resection.
Results: Of the 53 patients, 30 (57%) were diagnosed via non-surgical modalities including percutaneous needle biopsy (PCNB) (n=29) and transbronchial lung biopsy (TBLB) (n=1); and 23 (43%) were diagnosed by surgical modalities including video-assisted thoracoscopic wedge resection (n=22) and lobectomy (n=1). An initial clinical suspicion of a lung malignancy was associated with the use of surgical diagnostic approaches (P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/28416}
}