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The construction and analysis of the aberrant lncRNA-miRNA-mRNA network in non-small cell lung cancer

  
@article{JTD29105,
	author = {Xiaoyuan Wang and Hang Yin and Luquan Zhang and Dayong Zheng and Yingnan Yang and Jinfeng Zhang and Hao Jiang and Xiaodong Ling and Yanzhong Xin and Hao Liang and Chengyuan Fang and Jianqun Ma and Jinhong Zhu},
	title = {The construction and analysis of the aberrant lncRNA-miRNA-mRNA network in non-small cell lung cancer},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {5},
	year = {2019},
	keywords = {},
	abstract = {Background: Non-small cell lung cancer (NSCLC) is the most common cancer and the pathogenesis remain unclear. According to the competing endogenous RNA (ceRNA) theory, long noncoding RNA (lncRNA) have a competition with mRNAs for the connecting with miRNAs that affecting the level of mRNA. In this work, the ceRNA network and the important genes to predict the survival prognosis were explored.
Methods: In the study, we recognized differently expressed genes (mRNAs, lncRNAs and miRNAs) between NSCLC and normal tissues from The Cancer Genome Atlas database (fold change >2, P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/29105}
}