@article{JTD29197,
author = {Malgorzata Szolkowska and Ewa Szczepulska-Wojcik and Beata Maksymiuk and Barbara Burakowska and Sebastian Winiarski and Juliusz Gatarek and Piotr Rudzinski and Tadeusz Orlowski and Renata Langfort},
title = {Primary mediastinal neoplasms: a report of 1,005 cases from a single institution},
journal = {Journal of Thoracic Disease},
volume = {11},
number = {6},
year = {2019},
keywords = {},
abstract = {Background: This study was an epidemiological analysis of all primary mediastinal neoplasms (PMNs) diagnosed between 2000 and 2016 at the National Tuberculosis and Lung Diseases Research Institute, Poland.
Methods: All patients with any mediastinal abnormality were included in the analysis. The patients’ age and gender were obtained from the institutional database.
Results: From a cohort of 5,108 patients, 3,691 primary mediastinal lesions were found, including 1,005 (19%) PMNs: lymphomas (533, 53% of PMNs), thymomas (215, 21%), neurogenic tumors (NTs) (100, 10%), germ cell tumors (GCTs) (62, 6%), soft tissue tumors (STTs) (47, 5%) and thymic carcinomas/thymic neuroendocrine tumors (TCs/TNETs) (37 in total, 4%). The most frequent lymphomas were classical Hodgkin lymphomas [256] and primary mediastinal large B-cell lymphomas [163]. Type AB [73] predominated in thymomas and squamous cell carcinomas [9] and carcinoids [10] in TCs/TNETs. NTs encompassed mainly schwannomas [49], ganglioneuromas [21] and neurofibromas [10]. The most frequent STTs were hemangiomas [13] and lymphangiomas [11]. Lymphomas, thymomas and NT were more often in women, TCs/TNETs in men (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/29197}
}