@article{JTD29431,
author = {Yangsean Choi and Bo Mi Gil and Myung Hee Chung and Won Jong Yoo and Na Young Jung and Yong Hyun Kim and Soon Seog Kwon and Jeana Kim},
title = {Comparing attenuations of malignant and benign solitary pulmonary nodule using semi-automated region of interest selection on contrast-enhanced CT},
journal = {Journal of Thoracic Disease},
volume = {11},
number = {6},
year = {2019},
keywords = {},
abstract = {Background: The purpose of this study was to determine whether semi-automated region of interest (ROI) measurement of CT attenuations of solitary pulmonary nodule (SPN) is an accurate approach in differentiating malignant from benign SPN.
Methods: Ninety cases of pathologically proven SPN were retrospectively reviewed. CT attenuations of SPN before and after contrast injection were measured using semi-automated ROI selection method. Attenuations within a range of −100 to 200 Hounsfield units (HU) as soft tissue density range were set. The ROI included the entire SPN regardless of its internal soft tissue contents after automatic elimination of airs, calcific, or bony densities.
Results: There were 42 (46.7%) malignant SPN and 48 (53.3%) benign SPN, which were grouped into A (18 tuberculoma, 13 fungus), B (5 focal organizing pneumonia, 5 abscess), and C (7 other benign tumors). The malignant SPN showed significantly higher mean attenuations of enhancement and net-enhancement than all benign SPN (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/29431}
}