@article{JTD2982,
author = {Xiaorong Li and Danbing Shao and Gannan Wang and Ting Jiang and Honghao Wu and Bing Gu and Kejiang Cao and Jinsong Zhang and Lianwen Qi and Yan Chen},
title = {Effects of different LAD-blocked sites on the development of acute myocardial infarction and malignant arrhythmia in a swine model},
journal = {Journal of Thoracic Disease},
volume = {6},
number = {9},
year = {2014},
keywords = {},
abstract = {Objective: To explore the effects of various left anterior descending (LAD) artery-blocked sites on the development of acute myocardial infarction (AMI) and malignant arrhythmia in a swine model.
Methods: Twenty-two pigs underwent occlusion of the coronary artery with balloon angioplasty were randomly divided into three groups according to the blocked site of the balloon: middle-site-blocked LAD group, bottom-third-blocked LAD group and control group. Then, the development of AMI and malignant arrhythmia, including ventricular tachycardia and ventricular fibrillation during the process of model creation, were recorded. Changes of the hemodynamics, blood gas analysis, electrocardiography, and myocardial enzymes were analyzed in each group before and after occlusion.
Results: Middle-site-LAD blockage resulted in a larger infarction size and the corresponding incidence of ventricular fibrillation was significantly higher than that of the bottom-third-blocked group (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/2982}
}