@article{JTD3035,
author = {Yifeng Sun and Likun Hou and Huikang Xie and Hui Zheng and Gening Jiang and Wen Gao and Chang Chen},
title = {Wedge resection for localized infectious lesions: high margin/lesion ratio guaranteed operational safety},
journal = {Journal of Thoracic Disease},
volume = {6},
number = {9},
year = {2014},
keywords = {},
abstract = {Objective: This study aims to elucidate the risk factors of pulmonary complications for localized infectious lesions with limited resection.
Methods: We retrospectively investigated 139 cases for which wedge resection had been performed for localized pulmonary infectious lesions. Patients included 85 males and 54 females with a median age of 53 years (range: 21-74 years old). Forty-six patients had focal organizing pneumonia (OP), sixty patients had lung abscess, twenty-three patients had aspergilloma, five patients had lung abscess combining aspergillus fumigatus, and five patients had lung abscess combined with tuberculosis granuloma. Information regarding perioperative manipulations, surgical complications, and follow-ups were collected for further analysis.
Results: Prominent pneumonia developed in eight cases post-operation. In follow-up, one patient had a recurrence of lung abscess five months post-operation and underwent a left upper lobectomy and one patient died two months after discharge because of respiratory failure that resulted from pneumonia. Univariate and multivariate analysis showed a significant difference in the margin/lesion ratio (distance between staple margins to lesion/the maximum tumor diameter) between patients with pulmonary complications and those without complications (P=0.01). The best cut-off value of margin/lesion ratio to complication was 0.985, and a margin/lesion ratio less than 0.985 was associated with high post-operative complications.
Conclusions: The present case series shows that partial resection for localized pulmonary infection is an acceptable surgical manipulation. A high margin/lesion ratio achievement may guarantee operational safety.},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/3035}
}