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Quantifying the expression of tumor marker genes in lung squamous cell cancer with RNA sequencing

  
@article{JTD3038,
	author = {Lin Wang and Cheng Zhan and Yongxing Zhang and Jun Ma and Junjie Xi and Wei Jiang and Yu Shi and Qun Wang},
	title = {Quantifying the expression of tumor marker genes in lung squamous cell cancer with RNA sequencing},
	journal = {Journal of Thoracic Disease},
	volume = {6},
	number = {10},
	year = {2014},
	keywords = {},
	abstract = {Background: We measured the expression of some commonly used tumor markers with RNA sequencing (RNA-Seq) to identify any that might be useful for the evaluation of squamous cell lung cancer and identify possible correlations between these tumor markers and any clinical characteristics. 
Methods: RNA-Seq was performed on five pairs of squamous-cell lung cancer and normal tissues and another 39 squamous-cell lung cancer tissues obtained by our department between September and December, 2012. The expression of 13 commonly used tumor markers was determined. 
Results: All of the patients in our study were male. The expressions of CA125, CYFRA21-1, NSE and SCC increased in tumor samples and there were statistically significant differences between squamous cell lung cancer and normal tissues (P=0.008, P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/3038}
}