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PEEP titration guided by transpulmonary pressure: lessons from a negative trial

   
@article{JTD30855,
	author = {Fernando Suarez-Sipmann and Carlos Ferrando and Jesús Villar},
	title = {PEEP titration guided by transpulmonary pressure: lessons from a negative trial},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {Suppl 15},
	year = {2019},
	keywords = {},
	abstract = {Since the first description of the acute respiratory distress syndrome (ARDS) by the landmark paper of Ashbaugh et al. (1), the adequate use of positive end-expiratory pressure (PEEP) has been surrounded by a vivid controversy. This stems from the fact that its beneficial effects on oxygenation by re-aerating collapsed or flooded airspaces, may be counterbalanced by potential adverse effects on hemodynamics and on the risk of increasing lung tissue mechanical stress.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/30855}
}