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Cardiac obstruction secondary to metastatic invasion - A rare complication of Human Herpes Virus 8-positive plasmablastic lymphoma in acquired immunodeficiency syndrome

   
@article{JTD313,
	author = {Daniele Pádua and Ana Clara Rodrigues and Sérgio Barros and Ana Lúcia Arruda and Marianne Castro and José Lázaro Andrade},
	title = {Cardiac obstruction secondary to metastatic invasion - A rare complication of Human Herpes Virus 8-positive plasmablastic lymphoma in acquired immunodeficiency syndrome},
	journal = {Journal of Thoracic Disease},
	volume = {4},
	number = {4},
	year = {2012},
	keywords = {},
	abstract = {Human herpes virus 8 (HHV8)-positive plasmablastic lymphoma (PBL) is a particularly rare and aggressive subtype of non-Hodgkin lymphoma, strongly associated with human immunodeficiency virus infection, with poor response to therapy and short survival. Characteristically, it shows proliferation of large plasmablastic cells with often eccentrically placed nuclei, with immunohistochemical assay positive for HHV8 latent nuclear antigen 1 and IgM. Primary mediastinal occurrence of a HHV8-positive PBL is rare and metastatic disease even more uncommon; tumor invasion to the heart leading to intracardiac obstruction with a rapidly fatal disease course has not been previously described.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/313}
}