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Impact of clinical features on the efficacy of osimertinib treatment in epidermal growth factor receptor mutant non-small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors due to T790M mutation

   
@article{JTD31351,
	author = {Chong-Kin Liam and Mau-Ern Poh and Yong-Sheng Liam},
	title = {Impact of clinical features on the efficacy of osimertinib treatment in epidermal growth factor receptor mutant non-small cell lung cancer patients with acquired resistance to tyrosine kinase inhibitors due to T790M mutation},
	journal = {Journal of Thoracic Disease},
	volume = {11},
	number = {Suppl 15},
	year = {2019},
	keywords = {},
	abstract = {Epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) are the treatment of choice for patients with advanced stage non-small cell lung cancer (NSCLC) harboring EGFR sensitizing mutations (1,2). Before osimertinib, a third-generation EGFR-TKI, is recommended as the preferred agent in the first-line treatment in these patients, earlier generation TKIs such as erlotinib, gefitinib and afatinib, were the drug options available.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/31351}
}