@article{JTD3229,
author = {Ting Ye and Yunjian Pan and Rui Wang and Haichuan Hu and Yang Zhang and Hang Li and Lei Wang and Yihua Sun and Haiquan Chen},
title = {Analysis of the molecular and clinicopathologic features of surgically resected lung adenocarcinoma in patients under 40 years old},
journal = {Journal of Thoracic Disease},
volume = {6},
number = {10},
year = {2014},
keywords = {},
abstract = {Introduction: The youthful lung cancer may constitute an entity with distinct clinicopathologic characteristics and a controversial prognosis compared with the older counterpart. Whether the youthful lung cancer has the exclusively distinct molecular features has not been well investigated.
Methods: Thirty-six resected lung adenocarcinomas from young patients under 40 years old were analyzed concurrently for mutations in EGFR, KRAS, HER2, BRAF, AKT1, ALK, RET, TP53 and LKB1 and enrolled as the younger group. Their molecular and clinicopathologic characteristics were compared with those of 87 adenocarcinoma cases from patients above 40 years old which were collected as the older group.
Results: The comparable overall survival (OS) (P=0.942), more early adenocarcinomas (P=0.033), more wedge resections (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/3229}
}