@article{JTD32523,
author = {Hee Jung Kim and Seong Cheol Jeong and Jae Seung Jung and In Seup Kim and Choon-Hak Lim and Ho Sung Son},
title = {Renal hemodynamics by return cannular position of extracorporeal membrane oxygenation in swine},
journal = {Journal of Thoracic Disease},
volume = {11},
number = {10},
year = {2019},
keywords = {},
abstract = {Background: Whether arterial return cannula position affects the kidney during Veno-Arterial extracorporeal membrane oxygenation (ECMO) is unclear. Therefore, we compared hemodynamic parameters and acute kidney injury (AKI) biomarkers between ascending aorta return (aECMO) and femoral artery return ECMO (fECMO) in swine to evaluate the effect of cannula position on the kidney.
Methods: A total of twelve swines were allocated randomly into two groups. ECMO was maintained for 6h. Hemodynamic parameters including mean arterial pressure (MAP), renal arterial flow rate (AF), energy equivalent pressure (EEP), and surplus hemodynamic energy (SHE) were measured at the left renal artery. For evaluation of kidney injury, samples were obtained for blood urea nitrogen, creatinine, cystatin C, and neutrophil gelatinase-associated lipocalin (before ECMO, and 1, 3, and 6 h after initiating ECMO).
Results: Before the start of ECMO, hemodynamic parameters were not different between the two groups. With regard to the rate of change before and after ECMO, the fECMO group showed a significantly higher increase in MAP, AF, and EEP and a greater decrease in SHE than the aECMO group (P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/32523}
}