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Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparison of the clinicopathologic features and prognosis

  
@article{JTD3324,
	author = {Xia Li and Chang Chen and Jinfu Xu and Jinming Liu and Xianghua Yi and Xiwen Sun and Jingyun Shi},
	title = {Nonspecific interstitial pneumonia and usual interstitial pneumonia: comparison of the clinicopathologic features and prognosis},
	journal = {Journal of Thoracic Disease},
	volume = {6},
	number = {10},
	year = {2014},
	keywords = {},
	abstract = {Background: Nonspecific interstitial pneumonia (NSIP) has recently been proposed as a histologic type of idiopathic interstitial pneumonia (IIP), but its broad spectrum of clinicopathologic findings and variable prognosis are poorly understood. It is particularly unclear how NSIP and usual interstitial pneumonia (UIP) are related. The present study investigated the clinicopathologic features and prognosis of NSIP, and its differential diagnosis from UIP. 
Methods: The clinicopathologic findings and prognosis in 21 NSIP and 18 UIP patients who underwent surgical or video-assisted thoracoscopic lung biopsy were reviewed. 
Results: NSIP was more frequent in women and showed nonspecific clinical manifestations. Highresolution computed tomography (HRCT) demonstrated ground-glass, net-like, and patchy attenuation in both lungs. Semiquantitative HRCT showed a median fibrosis score of 3 (range, 0 to 7) in NSIP patients and 5 (range, 2 to 7) in UIP patients (P},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/3324}
}