@article{JTD3350,
author = {Yanfan Chen and Cheng Ding and Quan Lin and Kaiyan Yang and Yuping Li and Shaoxian Chen},
title = {Primary intravascular large B-cell lymphoma of the lung: a review and case report},
journal = {Journal of Thoracic Disease},
volume = {6},
number = {10},
year = {2014},
keywords = {},
abstract = {Objective: To investigate the clinicopathological features of primary intravascular large B-cell lymphoma (IVLBCL) of the lung.
Methods: Histopathological and clinical data based on lung biopsy were analyzed and used to diagnose a patient with IVLBCL of the lung.
Results: Fever and respiratory symptoms were the main presentations, lung biopsy revealed lymphoma cells in the lumen of small blood vessels. Tumor cells expressed Bcl-2, the Bcl-6, CD20, Ki67, MUM-1, Pax5, CD, CD30, and vascular endothelial CD34.
Conclusions: Primary pulmonary IVLBCL of the lung is extremely rare, on chest CT it manifests as diffuse ground glass shadow, or nodular consolidations in the lung, lactate dehydrogenase and C-reactive protein was found to increase, fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) is an important and significant diagnostic modality in its early diagnosis. Also, bronchial lung biopsy has the advantage of less trauma and high sensitive rate. R-CHOP is the main treatment for lung primary pulmonary IVLBCL of the lung; however, its prognosis is relatively poor.},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/3350}
}