%0 Journal Article
%T Preoperative hypoxemia in patients with type A acute aortic dissection: a retrospective study on incidence, related factors and clinical significance
%A Guo, Zijian
%A Yang, Yanwei
%A Zhao, Mingming
%A Zhang, Bo
%A Lu, Jiakai
%A Jin, Mu
%A Cheng, Weiping
%J Journal of Thoracic Disease
%D 2019
%B 2019
%9 
%! Preoperative hypoxemia in patients with type A acute aortic dissection: a retrospective study on incidence, related factors and clinical significance
%K 
%X Background: Pre-operative hypoxemia (HO) is a serious complication occurring in acute type A aortic dissection (AAD) patients.  Methods: This was a retrospective study of 505 patients who underwent Stanford type A acute aortic dissection surgery in Anzhen hospital, Beijing, China, between January 2015 to February 2018. Patients were divided into a HO(+) group (PaO2/FiO2 ≤300) and a HO(−) group (PaO2/FiO2 >300) according to preoperative arterial blood gas (ABG) analysis. The incidence of preoperative hypoxemia in patients undergoing surgery for AAD was calculated as the main outcome. Multivariable binary logistic regression analysis was used to identify independent prognostic factors of HO.  Results: Preoperative HO occurred in 46.5% (235/505) of patients. Mean patient age was 47.8±9.6 years, and 189 (80.4%) were male. Multivariable logistic regression analysis showed a correlation between preoperative serum level of fibrinogen [95% confidence interval (CI), 0.95–0.99], white blood cell count (WBC) (95% CI, 1.07–1.18), systolic blood pressure (95% CI, 0.98–1.00), history of smoking (95% CI, 1.05–2.11) and pleural effusion (95% CI, 1.14–2.71) with preoperative HO. The HO(+) group had a significantly higher mortality than the HO(−) group (8.1% vs. 5.9%, P=0.38). The median of intubation time (P
%U https://jtd.amegroups.org/article/view/34059
%V 11
%N 12
%P 5390-5397
%@ 2077-6624