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Overnight fluid shifts in subjects with and without obstructive sleep apnea

  
@article{JTD3466,
	author = {Ning Ding and Wei Lin and Xi-Long Zhang and Wen-Xiao Ding and Bing Gu and Bu-Qing Ni and Wei Zhang and Shi-Jiang Zhang and Hong Wang},
	title = {Overnight fluid shifts in subjects with and without obstructive sleep apnea},
	journal = {Journal of Thoracic Disease},
	volume = {6},
	number = {12},
	year = {2014},
	keywords = {},
	abstract = {Objective: To investigate the characteristics of baseline body fluid content and overnight fluid shifts between non-obstructive sleep apnea (non-OSA) and obstructive sleep apnea (OSA) subjects. 
Methods: A case-controlled study was performed between February 2013 and January 2014, with 36 (18 OSA and 18 non-OSA) outpatients enrolled in this study. Polysomnographic parameters and results of body fluid were compared between the two groups. 
Results: There were no differences in age, weight, and body mass index (BMI) between groups. Compared with the non-OSA group, OSA group had significantly higher neck circumference (NC) and fluid volume shift in the legs. OSA patients had higher left and right leg fluid indices than non-OSA subjects. There were significant correlations between apnoea-hypopnoea index and baseline fluid indices in both legs as well as the reduction in overnight change in both legs fluid volume. The increase in NC was also significantly correlated with the reduction in overnight change in both legs fluid volume, but not with the change in head and neck fluid volume. There were significant correlations between change in NC and increased fluid shifts in head and neck volume. 
Conclusions: OSA patients had a higher baseline fluid content in both legs as compared with non-OSA subjects, which may be the basic factor with regards to fluid shifts in OSA patients. The increase in head and neck fluid shift volume did not directly correlate with the severity of OSA.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/3466}
}