@article{JTD352,
author = {Allan Y. Chen and Michelle B. Chen and Yi-Jen Chen},
title = {A millimeter miss is as good as a thousand miles: The role of accurate target localization in lung stereotactic body radiation therapy},
journal = {Journal of Thoracic Disease},
volume = {4},
number = {2},
year = {2012},
keywords = {},
abstract = {Surgical intervention with lobectomy and mediastinal lymph node dissection is considered the treatment of choice in early stage non-small cell lung cancer (NSCLC) (1). However, approximately 20-25% of patients with early stage NSCLC are poor surgical candidates for lobectomy because of concomitant severe cardiac or pulmonary co-morbidities. For these patients, conventional radiotherapy with 60 to 70 Gy delivered in 30-35 fractions over a 6-7-week period generally resulted in poor 20-40% 3-year and 10-30% 5-year survival rates (2,3). This inadequate tumor control is mainly due to the insufficient tumor dose that is limited by normal tissue toxicity and possible target-miss caused by tumor mobility.},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/352}
}