TY  - JOUR
AU  - Charalampidis, Charalampos
AU  - Youroukou, Andrianna
AU  - Lazaridis, George
AU  - Baka, Sofia
AU  - Mpoukovinas, Ioannis
AU  - Karavasilis, Vasilis
AU  - Kioumis, Ioannis
AU  - Pitsiou, Georgia
AU  - Papaiwannou, Antonis
AU  - Karavergou, Anastasia
AU  - Tsakiridis, Kosmas
AU  - Katsikogiannis, Nikolaos
AU  - Sarika, Eirini
AU  - Kapanidis, Konstantinos
AU  - Sakkas, Leonidas
AU  - Korantzis, Ipokratis
AU  - Lampaki, Sofia
AU  - Zarogoulidis, Konstantinos
AU  - Zarogoulidis, Paul
PY  - 2015
TI  - Physiology of the pleural space
JF  - Journal of Thoracic Disease; Vol 7, Supplement 1 (February 05, 2015): Journal of Thoracic Disease [(dedicated to) 2014 Pan Hellenic Congress on Respiratory and Occupational Chest Diseases]
Y2  - 2015
KW  - 
N2  - The pleural cavity is created between the 4th and 7th week of embryologic development. These embryonic components of visceral and parietal pleurae develop different anatomic characteristics with regard to vascular, lymphatic, and nervous supply. There are two layers: a superficial mesothelial cell layer facing the pleural space and an underlying connective tissue layer. The pleura might present inflammatory response and maintenance of the pleural fluid is observed. The latter function is especially important in the mechanical coupling of the lung and chest wall. Fluid is filtered into the pleural space according to the net hydrostatic oncotic pressure gradient. It flows downward along a vertical pressure gradient, presumably determined by hydrostatic pressure and resistance to viscous flow. There also may be a net movement of fluid from the costal pleura to the mediastinal and interlobar regions. In these areas, pleural fluid is resorbed primarily through lymphatic stomata on the parietal pleural surface. In the current review we will present the physiology of the pleural space in a step by step manner.
UR  - https://jtd.amegroups.org/article/view/3848