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Individualizing adjuvant therapy for early stage non-small cell lung cancer: we see the destination, but we don’t yet know the route

   
@article{JTD4149,
	author = {Howard West},
	title = {Individualizing adjuvant therapy for early stage non-small cell lung cancer: we see the destination, but we don’t yet know the route},
	journal = {Journal of Thoracic Disease},
	volume = {7},
	number = {3},
	year = {2015},
	keywords = {},
	abstract = {Though the survival benefit of adjuvant therapy for at least stage II-IIIA non-small cell lung cancer (NSCLC) has been demonstrated in multiple prospective randomized phase III trials, we should recognize that our approach to post-operative management of early stage NSCLC is relatively primitive. In hopes of curing more patients, we recommend a challenging, toxic therapy to all fit patients, despite understanding that many should already be cured with no further therapy. Moreover, we can readily appreciate that platinum-based doublet therapy is far more effective for some patients than for others and that, as we have now entered an era of molecularly-guided oncology treatment, specific targeted therapies may be far superior to conventional chemotherapy for prospectively identified populations.},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/4149}
}