@article{JTD512,
author = {Jian Wang and Yun Ma and Zhi-Hua Zhu and Dong-Rong Situ and Yi Hu and Tie-Hua Rong},
title = {Expression and prognostic relevance of tumor carcinoembryonic antigen in stage IB non-small cell lung cancer},
journal = {Journal of Thoracic Disease},
volume = {4},
number = {5},
year = {2012},
keywords = {},
abstract = {Background: High serum carcinoembryonic antigen (CEA) levels have been reported to be associated with poor prognosis
in non-small cell lung cancer (NSCLC), while the prognostic role of tumor CEA expression remains to be defined. The
present study investigated the expression of tumor CEA in stage IB NSCLC, and correlated it with clinicopathological
features and prognosis.
Patients and methods: Immunohistochemistry for tumor CEA was assessed in the specimens of 183 patients with stage
IB NSCLC. Receiver-operating characteristic (ROC) curve analysis was used to determine the cut-off score for tumor
positivity.
Results: High CEA expression was detected more frequently in adenocarcinomas (72.2%) and other NSCLCs (69.0%)
than in squamous cell carcinomas (25.4%, P},
issn = {2077-6624}, url = {https://jtd.amegroups.org/article/view/512}
}