How to cite item

EGFR inhibition and more: a new generation growing up

   
@article{JTD577,
	author = {Deborah Enting and James Spicer},
	title = {EGFR inhibition and more: a new generation growing up},
	journal = {Journal of Thoracic Disease},
	volume = {4},
	number = {6},
	year = {2012},
	keywords = {},
	abstract = {The discovery of activating epidermal growth factor receptor (EGFR) mutations in non-small cell lung cancer (NSCLC) has led to a shift in treatment paradigm for some patients with advanced disease. Mutations in exons 18-21 in the tyrosine kinase domain are associated with improved clinical outcomes following treatment with tyrosine kinase inhibitors (TKIs). The first-generation EGFR TKIs erlotinib and gefitinib are most effective in the presence of EGFR mutations (1).},
	issn = {2077-6624},	url = {https://jtd.amegroups.org/article/view/577}
}